Prostate Cancer Assignment Paper

Prostate Cancer Assignment Paper

Prostate Cancer Assignment Paper
Prostate cancer is one of the most common forms of cancer diagnosed in men, second to skin cancer.Prostate Cancer Assignment Paper Although causative factors are still being studied and explored, prostate cancer is thought to be dependent upon hormones, with links found between advanced age and androgens. It has been found that increased estrogen and decreased dihydrotestosterone (DHT) related to age have strong correlations with prostate cancer. It is the increase in estrogen that creates the problem, as testosterone is known to cause prostate hypertrophy but not malignancy.Prostate Cancer Assignment Paper Other theories describe repeated injury to the prostate’s epithelium by means of carcinogens, toxins, autoimmune diseases, and inflammation. This repeated injury causes a hyper prolific state that can translate to cancer (Huether & McCance, 2017).

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Early screening is preferred because symptoms usually do not occur until advanced disease. Screening is performed by digital rectal exam and serum PSA levels. Prostate cancer will metastasize to the pelvis, bowel, lymph, rectum, and spine (Arcangelo, Peterson, Wilbur, & Reinhold, 2017).Prostate Cancer Assignment Paper
Treatment
Treatment can include surgical prostatectomy, pharmacotherapy, chemotherapy, radiation, or a combination, dependent upon stage and type (Arcangelo, Peterson, Wilbur, & Reinhold, 2017). Since prostate cancer needs androgens to grow, androgen deprivation therapy (ADT) is the first line of treatment.Prostate Cancer Assignment Paper These medications can prevent the cancer cells from receiving testosterone or reduce the amount of testosterone made altogether and ultimately slow down and/or reduce the size of the tumor.

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It is not a cure and many side effects can be unpleasant, including hot flashes, erectile dysfunction, osteopenia, increase in adipose tissue and weight gain (Drugs.com, 2012).Prostate Cancer Assignment Paper Eventually, the cancer will become “castration resistant” and treatment options will need to change, mostly including novel androgen receptor targeting
agents and chemotherapy (Shiota & Eto, 2016). Patients should be educated on the need for long term treatment, medication side effects, and medication importance in order to increase compliance.Prostate Cancer Assignment Paper

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