1. What is the role of oligosaccharides such as galacto-oligosaccharides (GOS) and fructooligosaccharides (FOS) in the health and wellbeing of infants and indicate if there are any potential safety issues that may determine upper limits of addition to infant formulas? 2. Outline the weight of scientific evidence for a clinical benefit of oligosaccharide supplementation on infant health and wellbeing compared to formula without oligosaccharides. For this part, you need to take into account both positive (studies that show a benefit) and negative research (studies that didn’t show a benefit) and use the literature to develop an argument to inform your conclusion in part 3. – If evidence is coming from large-scale long-term human randomised-controlled trials (RCTs) then this would be considered stronger evidence than studies conducted in animals or from observational research (such as cohort, case-control or cross-sectional studies). – Evidence from systematic reviews and/or meta-analyses of RCTs are generally considered to be the highest form of evidence. – Almost all the references for your report should be coming from peer-reviewed scientific studies. If you mostly use websites as references then expect to be heavily marked down. – You may need to consider different categories of infants (e.g. term vs pre-term infants) in considering the weight of evidence, but this would be your decision

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