FDA usually requires two animal models. You will need to get IACUC approval for two different animal models. You need to make sure you reference all facts from Pubmed, with a reference list at the end of your answer. Questions: This criterion is linked to a Learning Outcome1. List two animal models for your disease if they exist ,with references. If one or both models do not currently exist, you can list an animal model that you will develop. (The instructors will used PubMed to make sure an animal model does not exist)Gives a full, complete answer with references Full Marks Answers the question completely, using references. Partial Answer Gave a partial answer, but does not address each portion of the question or does not use appropriate references. No Marks Did not address the question. 2 pts This criterion is linked to a Learning Outcome2A. Which of the two animal model species in question 1 will you be using? Or, what animal species will you use develop your own animal model?Gives a full, complete answer with references Full Marks Answers the question completely, using references. Partial Answer Partial answer, didn’t list species No Marks Did not address the question. 1 pts This criterion is linked to a Learning Outcome2B. How is the animal given the disease in the existing model? Or how will you administer the disease to the animals, and in what dose in your own model.Gives a full, complete answer Full Marks Answers the question completely, addressing each point and using references. Minor issue A minor point is incorrect or missing. Partial Answer Gave a partial answer, but does not address each portion of the question or does not use appropriate references. No Marks Did not address the question. 4 pts This criterion is linked to a Learning Outcome2C. In what ways does the existing model resemble human disease AND in what ways is it different? Or describe the ways in which will you test your new model to determine if it resembles human disease?propertyGives a full, complete answer with appropriate references Full Marks Answers the question completely, using clear logic and references if necessary. Minor issue A minor point is incorrect or missing. Partial Answer Gave a partial answer, but does not address each portion of the question using clear logic, or does not use supporting references. No Marks Did not address the question. 5 pts This criterion is linked to a Learning Outcome2D. What will you monitor in the animals during the disease progression? What is the final end point?Gives a full, complete answer with appropriate references. Full Marks Answers the question completely, using clear logic, and references if necessary. Minor issue A minor point is incorrect or missing. Partial Answer Gave a partial answer, but does not address each portion of the question using clear logic, or does not use supporting references. No Marks Did not address the question. 4 pts This criterion is linked to a Learning Outcome3A. Approximately many animals will you use of each of the two species and why?Gives a full, complete answer with references Full Marks Answers the question completely, using references. Partial Answer Gave a partial answer, but does not address each portion of the question or does not use appropriate references. No Marks Did not address the question. 2 pts This criterion is linked to a Learning Outcome3B. Where will the animals be housed?Gives a full, complete answer with references Full Marks Answers the question completely, using references. Partial Answer Gave a partial answer, but does not address each portion of the question or does not use appropriate references. No Marks Did not address the question. 2 pts This criterion is linked to a Learning Outcome3C. How will you monitor them for disease and how often will you check on them?Gives a full, complete answer with references Full Marks Answers the question completely, using references. Partial Answer Gave a partial answer, but does not address each portion of the question or does not use appropriate references. No Marks Did not address the question. 3 pts This criterion is linked to a Learning Outcome3D. Do you have to make any special arrangements to use these animal models? Housing, space, play, diet, restricted movement?Gives a full, complete answer with references Full Marks Answers the question completely, using references. Partial Answer Gave a partial answer, but does not address each portion of the question or does not use appropriate references. No Marks Did not address the question. 2 pts Total Points: 25 List two animal models for your disease if they exist ,with references. If one or both models do not currently exist, you can list an animal model that you will develop. (The instructors will used PubMed to make sure an animal model does not exist) (2 points) Choose one of these animal models and address the following questions
Which of the two animal model species in question 1 will you be using? Or, what animal species will you use develop your own animal model? (1 point)
How is the animal given the disease in the existing model? Or how will you administer the disease to the animals, and in what dose in your own model. (4 points)
In what ways does the existing model resemble human disease AND in what ways is it different? Or describe the ways in which will you test your new model to determine if it resembles human disease? (5 points)
What will you monitor in the animals during the disease progression? What is the final end point? 94 points) Which of the two animal model species in question 1 will you be using? Or, what animal species will you use develop your own animal model? (1 point) How is the animal given the disease in the existing model? Or how will you administer the disease to the animals, and in what dose in your own model. (4 points) In what ways does the existing model resemble human disease AND in what ways is it different? Or describe the ways in which will you test your new model to determine if it resembles human disease? (5 points) What will you monitor in the animals during the disease progression? What is the final end point? 94 points) Describe your application to IACUC for animal use –
Approximately many animals will you use of each of the two species? (2 points)
Where will they be housed? (2 points)
How often will you monitor them for disease? (3 points)
Do you have to make any special arrangements to use these animal models? Housing, space, play, diet, restricted movement? (2 points) Approximately many animals will you use of each of the two species? (2 points) Where will they be housed? (2 points) How often will you monitor them for disease? (3 points) Do you have to make any special arrangements to use these animal models? Housing, space, play, diet, restricted movement? (2 points) List two animal models for your disease if they exist ,with references. If one or both models do not currently exist, you can list an animal model that you will develop. (The instructors will used PubMed to make sure an animal model does not exist) (2 points) Choose one of these animal models and address the following questions
Which of the two animal model species in question 1 will you be using? Or, what animal species will you use develop your own animal model? (1 point)
How is the animal given the disease in the existing model? Or how will you administer the disease to the animals, and in what dose in your own model. (4 points)
In what ways does the existing model resemble human disease AND in what ways is it different? Or describe the ways in which will you test your new model to determine if it resembles human disease? (5 points)
What will you monitor in the animals during the disease progression? What is the final end point? 94 points)
Describe your application to IACUC for animal use –
Approximately many animals will you use of each of the two species? (2 points)
Where will they be housed? (2 points)
How often will you monitor them for disease? (3 points)
Do you have to make any special arrangements to use these animal models? Housing, space, play, diet, restricted movement? (2 points) Which of the two animal model species in question 1 will you be using? Or, what animal species will you use develop your own animal model? (1 point)
How is the animal given the disease in the existing model? Or how will you administer the disease to the animals, and in what dose in your own model. (4 points)
In what ways does the existing model resemble human disease AND in what ways is it different? Or describe the ways in which will you test your new model to determine if it resembles human disease? (5 points)
What will you monitor in the animals during the disease progression? What is the final end point? 94 points) Approximately many animals will you use of each of the two species? (2 points)
Where will they be housed? (2 points)
How often will you monitor them for disease? (3 points)
Do you have to make any special arrangements to use these animal models? Housing, space, play, diet, restricted movement? (2 points)
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